What is it?
The number of fertile eggs a woman has at any given time will be a determining factor in achieving pregnancy, both naturally and through assisted reproduction techniques.
The ovarian reserve is measured through the Antimullerian Hormone (AMH) level, which reliably determines a woman’s ovarian reserve, that is, the quantity and quality of fertile eggs she has.
Useful information
During childhood, ovarian reserve levels are low, and from puberty onwards, they begin to increase as ovulation begins. They usually peak between the ages of 22 and 25 and then gradually decline. From the age of 35, they decrease very rapidly until they disappear completely at menopause.
In women, AMH plays a key role in folliculogenesis and reflects the number of antral and prenatal follicles. Serum AMH levels correlate with the number of primordial follicles in the ovaries and allow reliable determination of fertility potential.
Indications
This test is suitable for all women who want to know their ovarian reserve, and helps to plan their childbearing earlier and with a better chance of success.
It is also used for:
- Menopause: predicting the onset of menopause, when a woman stops having menstrual periods.
- Early menopause: diagnosis of early ovarian failure.
- Polycystic ovary: provides information on polycystic ovary syndrome (PCOS).
- Fertility: complementary information for the diagnosis and choice of the most effective treatment for couples with fertility problems.
- In Vitro Fertilisation (IVF): the identification of patients with low or high response before treatment with controlled stimulation reduces both the failure rate and the risk of ovarian hyperstimulation.
Results
Concordance between Antral Follicle Count (AFR) and serum AMH levels:
| AFR 0-7 | AFR 8-15 | AFR > 15 | |
|---|---|---|---|
| AMH 4.86 pmol/L (0.681 ng/mL) | 63.2% | 32.4% | 4.4% |
| AMH 4.87 – 16.2 pmol/L (0.682 ng/mL-2.27 ng/mL) | 12% | 56.9% | 31.1% |
| AMH > 16.2 pmol/L (>2.27 ng/mL) | 1.4% | 24.1% | 74.5% |
Patients with low AMH values
(≤ 4.86 pmol/L; 0.681 ng/mL)
Ο Probability of low AFR values (0-7) is 63%.
Ο Probability of medium PAR values (8-15) is 32%.
Ο Probability of high PAR values > 15 is 4.4%.
Patients with high AMH values
(> 16.2 pmol/L; 2.27 ng/mL)
Ο Probability of high PAR values (> 15) is 75%.
Ο Probability of medium PAR values (8-15) is 24%.
Ο Probability of low PAR values (<8) is 1.4%.
| pmol/L | ng/mL | |
|---|---|---|
| Men | 10.20 – 82.80 | 1.43 – 11.60 |
| Women 20 – 24 years | 10.90 – 71.00 | 1.52 – 9.95 |
| Women 25 – 29 years | 8.57 – 64.60 | 1.20 – 9.05 |
| Women 30-34 years | 5.08 – 54.20 | 0.71 – 7.59 |
| Women 35 – 39 years | 2.89 – 49.70 | 0.41 – 6.96 |
| Women 40 – 44 years | 0.42 – 31.70 | 0.06 – 4.44 |
| Women 45 – 50 years | 0.07 – 12.80 | 0.01 – 1.79 |
| Response to ovarian stimulation HIGH |
> 15.00 | > 2.10 |
| Polycystic Ovarian Syndrome | 17.20 – 122.00 | 2.41 – 17.10 |
Process
It requires a simple blood sample.
Receipt of the sample in our laboratory.
Results available within 3 working days.
Online study report.
- It should be performed on any day of the menstrual cycle.
- Fasting is not necessary.